British Prime Minister Theresa May's "Brexit" deal -- a negotiated deal for Britain to LEAVE the European Union (EU) -- has been rejected by 230 votes - the largest defeat for a sitting government in history.
MPs voted by 432 votes to 202 to reject the deal, which sets out the terms of Britain's exit from the EU on 29 March.
Labour leader Jeremy Corbyn has now submitted a vote of no confidence in the government, which could trigger a general election.
The confidence vote is expected to be held at about 1300 Local time on Wednesday.
Mr Corbyn said it would allow the House of Commons to "give its verdict on the sheer incompetence of this government."
The DUP's Brexit spokesman Sammy Wilson said his party would be supporting Mrs May in Wednesday's confidence vote.
He said: "We want to see the Conservative government continuing to deliver on Brexit.
"We never wanted a change of government, we wanted a change of policy back to what the prime minister promised in the manifesto she stood on, and the promises she made in subsequent speeches."
If MPs vote to back a no confidence motion, the government, or anyone else who can command a majority, would get 14 days to win a further confidence vote. If they can't win that, a general election will be then held.
Some 118 Conservative MPs voted with the opposition parties against Mrs May's deal.
Almost two years ago the British people held a Referendum on whether or not their country should remain in the European Union. Like polling in the US which erroneously projected Hillary Clinton to win, polls in Britain erroneously projected people would vote to REMAIN. They didn't.
The vote to Exit the EU sent a political shockwave across Britain and across Europe.
Former Prime Minister David Cameron, under whose administration the vote took place, said he could not in good conscience be the man to steward Britain out of the EU, and he resigned.
Theresa May was then elected Prime Minister, pledging to strike a deal with Europe. But the Europeans were not in a dealing mood.
Petty and vindictive that Britain would even desire to leave the EU, and determined to hurt Britian for doing so, the Europeans adopted a hard-line approach to negotiations. Those negotiations formed a "deal" that would effectively make Britain a vassal state of the EU. It was that deal which the British Parliament REJECTED today.
The hard deadline for Britain to leave the EU is March 29.
If there is no deal, issues of travel and trade between Britain and Europe would -- presumably -- fall under the World Trade Organization, but that is not guaranteed.
Today's vote sends the entire notion of "BREXIT" into chaos, and as of today's vote, it appears Theresa May will lose her job as Prime Minister as early as tomorrow.